Natural antibiotics like garlic (allicin), raw honey, and oregano oil demonstrate genuine antimicrobial activity in peer-reviewed studies. This evidence-based guide examines 12 natural antibiotics with the strongest research backing, including specific dosing protocols, preparation methods that maximize potency, and critical safety boundaries. Learn which natural antibiotics work for respiratory infections, wound healing, and digestive pathogens—plus medication interactions that matter, essential oil safety protocols, and clear medical intervention thresholds. Includes comparison tables matching natural antibiotics to specific infections, cost-effectiveness analysis, and a systematic framework for building personalized protocols. Natural antibiotics complement medical care for minor infections when used responsibly, but cannot replace prescription antibiotics for serious bacterial infections like pneumonia or sepsis.